TMBCAT: A MULTI-ENDPOINT P-VALUE CRITERION ON DIFFERENT DISCREPANCY METRICS FOR SUPERIORLY INFERRING TUMOR MUTATION BURDEN THRESHOLDS

TMBcat: A multi-endpoint p-value criterion on different discrepancy metrics for superiorly inferring tumor mutation burden thresholds

Tumor mutation burden (TMB) is a widely recognized stratification biomarker for predicting the efficacy of immunotherapy; however, the number and universal definition of the categorizing thresholds remain debatable due to the multifaceted nature of efficacy and the imprecision of TMB measurements.We proposed a minimal joint p-value criterion from t

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Livestock Performance for Sheep and Cattle Grazing Lowland Permanent Pasture: Benchmarking Potential of Forage-Based Systems

Here we describe the livestock performance and baseline productivity over a two-year period, following the establishment of the infrastructure on the North Wyke Farm Platform across its three farmlets (small farms).Lowland permanent pastures were continuously stocked with yearling beef cattle and ewes and their twin lambs for two years in three far

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